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Part of me wants to say yes because I don't like the idea of a trans voice. There are some manly women and some really girly sounding dudes out there. Your voice is your voice. Just own it.
The other part of me wants to say who the fuck knows, because even if you audition you get zero feedback and you're left in the dark.
If you're doing Hololive then you'd better be upfront about being a tranny. If you hide that shit everyone will hate you when they find out. Just saying.