>>52556269hires fix is much more customizable than webui since you can keep upscaling the image beyond one iteration. essentially you can just build your own version of hires fix. i haven't tried it but you can for example chain together two different types of filtering and combine something like 2x + 3x = 6x upscaling if you really wanted to
there's a lot more image postprocessing effects if you want something that changes the color/saturation/etc.
otherwise a lot of the features from A1111 have been carried over, the main ability you've gained is changing how the underlying image generation behaves
there are lots of people on the comfyui matrix chat that experiment more than i do so you can check out their workflows for ideas (mostly I'm comfortable with having txt2img with a prompt queue for the time being)