Fun fact about this particular show - it's a great example of how ironic humor becomes unironic, and how original creative intent dies whenever big money gets involved. Here's a little history lesson for you.
The original short, called simply "The Annoying Orange", was released in 2009, (so it's not as old as some people might think it is, a lot of Internet animation predates it actually), and you wouldn't find it on the official channel, of course
https://www.youtube.com/watch?v=ZN5PoW7_kdA - here it is. It was released on the creator's own channel, and you'll find that it's not even the first Clutch Cargo-style animation he did, far from it.
The idea was not to make an entertaining show about fruits. It was, in fact, a parody. A parody of low-budget children shows you'll find on PBS and what have you back in the late 20th century, all excessively annoying and often downright ugly, made not to teach kids anything, but rather to serve as a digital equivalent of dangling keys in front of them to get those sweet-sweet TV ratings. Annoying Orange was intended to be a one-off too. The joke was simple - make something very much brainless, annoying, but at the same kind of dark for adults (and make no mistake, this was a video for adults, not kids) to point and laugh at how ridiculous things they watched in their early childhood really were. Of course, the original video became a success, so more videos were made, and eventually the entire channel was created. Annoying Orange went from a tiny parody project to a mainstream show, and that's when a curious transformation occurred.
It became a show for children. Even though it didn't change much. It became a thing it was parodying - a dumb, ugly show to dangle in front of the very little kids to entertain them for exactly 5 minutes at a time to get that sweet-sweet ad revenue. Eventually, it even got a Cartoon Network spot, where it failed miserably (trashed by everyone and cancelled after only two seasons), which is not exactly surprising - the original was supposed to be a self-aware insult to the audience's intelligence, but by the time it got on Cartoon Network, the insult was played very straight, with zero self-awareness involved. And at this point, Annoying Orange was milked for all its worth - the original channel exists exclusively to farm views from the YouTube Kids app, all but dead in the public consciousness, sitting on the same shelf as endless Spider-Man and Elza videos and finger family songs. Obviously, the original creator is barely involved too - he only voices the characters, without writing or filming anything. Annoying Orange originally was a fun parody of the soulless and trashy programming of old, made on a platform where lots of fresh faces were getting their start in the new entertainment industry. But it ended up becoming a prime example of this new industry's soulless and trashy programming.
Ironic indeed.