I thought about this when she talked about never taking pills, but Ame has some weird ideas about how drug tolerance works
https://www.youtube.com/watch?v=6gFe6V3rSAwLike, a bottle of iced tea is probably the equivalent of a sip of coffee maybe, and it's not like a cup of coffee is actually going to actually keep you awake if you're really sleepy anyway. Same with the painkiller thing and thinking they are going to be really effective because she never takes them. Maybe if you abuse them daily you build a tolerance, but a tylenol is not going to be as effective as morphine because you haven't taken one in years.
I mean, it probably does work on her to some extent due to placebo effect, maybe, but she's probably pushing through on some really bad head/tummy aches for no reason.