>>4999687You know hereditary mental illnesses exist, right, Anon? It's not just an imaginary experience but an innate biological deficiency or a environmental and contextual pressure that has compounding negative effects on the function of the brain and body.
The stress, for example, of extreme isolation can change your brain such that it becomes impossible to fully reintegrate into society because of the manner in which certain neurological functions become impaired.
An explicit consequence of prolonged stress which causes your body to flood itself with hormones like Cortisol.
Why do you think Nasa invests so much money into researching the effects of isolation on Astronauts? Because the mental duress of a journey, to say Mars, would otherwise result in them trying to kill each other first. (This is of course one example of how stress can be induced but my point is fundamentally that it's not an fantastical concept by any stretch)