>>8086885For EN, it's hard not to recommend all of them, as they'll often guerilla into each others' streams far more often than you might think and the pleasantness of their chemistry scales with how many of them you actively engage with. You can decide who you like the most from there.
For ID/KR I like Bora Nun for her APEX skill, Jiyu Oh because she's hot as fuck, Lee Roha who's a hidden gem, Hyona Elatiora and Azura for the deeper, smoother voices.
JP is where you'll have to do a lot of trial and error for yourself, though. There's someone for everyone (and in a lot of cases, multiple), but Ange Katrina, Higuchi Kaede, Sara Hoshikawa, Kanae, and Kuzuha are all really good entryways into Nijisanji.
My personal picks outside of that would be Kitakoji Hisui, Belmond Banderas, Inui Toko (for her singing), Suzuka Utako, Kagami Hayato, and Matsukai Mao.
If you want to meet the true final boss of V-Tubing then your free to check out whatever wacky bullshit Fumino Tamaki is up to.