>>94024672youtube and most adblockers are in a constant arms race. there was a period about a year back where youtube broke adblockers for like a month and only let people with adblockers watch 3 videos a day before preventing videos from loading as long as the adblocker was turned on. usually though, whatever change they make all of the adblockers jump to update in a few hours.
What twitch does is it has about a bazillion url hosts under the AWS that they stream their ads from and they change it CONSTANTLY. This prevents most common adblockers from being able to lock in and block a given url, because by the time they have made the change on their side twitch is already two steps ahead.
The simple solution is to use a more hardcore scriptblocker that has a whitelist and blocks EVERYTHING you dont permit, and then you manually permit twitch and a few scripts that it checks to function, while keeping the actual ad sources blocked no matter what they change to. But this is beyond the expectations of the average internet user.