>>7693229Drop about 1000 micrograms of LSD. Wait an hour and eat about 10 grams of dried shrooms. Give it about another hour or two. Smoke some top grade herb with hash crumbles mixed in while waiting. Then do a few blasts of nitrous. Pace yourself on the nitrous. Remember to breath normally for a couple of minutes between blasts. This isn't about the destination, it's about the journey.
If you don't actually fold space, you'll have a good enough idea to imagine it. And, keep in mind that the Bene Gesserit do the same thing on less spice and don't need to actually mutate. Physically.