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I don't know a ton but I do know this much:
It comes from Nikke. The pink girl is named Dorothy and is the origin of it, hence Doro.
I did a little search and found this from the forbidden R-word website:
"Doro is a meme that may have come from the South Korean fanbase. Some artists saw that Dorothy is cute but actually psychotic. She schemes like a gremlin, so she became a gremlin. Also, taking the psychotic and deranged scheming character and turning her into a poorly drawn and funny meme is funny."
