>>477798There's another layer of commentary there, in the way they chose express the feeling of hopelessness. By using this old paradox as a framing device they show that the advice is in itself nonsensical and impossible to apply practically, and also demonstrate that people who obsess over it are in fact wasting their time. Pepe in the last panel tells Wojack that his observation that the expression never contains any meaning "serves a little to right his course" but Wojack is too caught up in his despair to realize Pepe is telling him that recognizing the futility of the puzzle is the first step to moving past it.