/bant/ - International/Random » Thread #17926367

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Anonymous ID:9eKKZDkh Fri 23 Jun 2023 08:23:08 No.17926367 View View Reply Original Report

Quoted By:

Delete /pol/.

Akariman !!PfcppGG/dig

Akariman !!PfcppGG/dig ID:x/70OMrW Fri 23 Jun 2023 08:25:35 No.17926373 Report

Quoted By:

The person posting was a russian bot and is therefore a computer and has no mRNA however.

Anonymous

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Anonymous ID:JNLRzCXu Fri 23 Jun 2023 08:28:03 No.17926382 Report

Quoted By: >>17926397

i'm tired of brainlets using words such as mRNA without any sensible context other than assuming their message is related to covid vaccine tech.

speaking of these vaccines, what cells does the vaccine dose target exactly? what cells receive the mRNA and start producing antigens? via quick google search atm i can only find stuff like "Upon delivery of an mRNA vaccine encoding a target antigen, cells will take up the mRNA and translate it into protein in situ." but no explanation what kind of cells

Anonymous

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Anonymous ID:JNLRzCXu Fri 23 Jun 2023 08:33:51 No.17926397 Report

Quoted By: >>17926399

>>17926382
ok i think i found a paper explaining it. so it's received directly by immune system cells, pretty cool

Anonymous

Anonymous ID:JNLRzCXu Fri 23 Jun 2023 08:35:30 No.17926399 Report

Quoted By:

>>17926397
>Either mRNA-LNPs or locally produced antigen are taken up by antigen-presenting cells (APCs)
ok so there is "either" and talk about locally produced antigens. so it's still not clear what are ALL the cell types that can receive the mRNA-LNP vector

Anonymous

Anonymous ID:JNLRzCXu Fri 23 Jun 2023 08:47:03 No.17926419 Report

Quoted By:

Ok I think I wouldn't be that worried.

>In this study we present evidence that COVID-19 mRNA vaccine BNT162b2 is able to enter the human liver cell line Huh7 in vitro. BNT162b2 mRNA is reverse transcribed intracellularly into DNA as fast as 6 h after BNT162b2 exposure [1]
>A previous study on mRNA vaccines against H10N8 and H7N9 influenza viruses using a similar LNP delivery system showed that the mRNA vaccine can distribute rather nonspecifically to several organs such as liver, spleen, heart, kidney, lung, and brain, and the concentration in the liver is roughly 100 times lower than that of the intra-muscular injection site [1]

[1] https://www.mdpi.com/1467-3045/44/3/73

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