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I'm a 1/18 scale (4") lover, because they get vehicles and scenery. 1/12 (6") isn't bad for characters and can have better accessories than 1/18, but rarely get vehicles (usually just bikes), much less scenery. 1/6 (12") is pretty bitchin' in terms of accessories, and even get clothing! But usually suck balls in terms of playability, and most of the time have alright articulation.
Mega construx has really cool Minifigures, with interchangeable armors, so I'd like to see someone try such a scale, but without the "Lego" aspect, so we get straight vehicles and shit that aren't all block and studs-y.