Maybe. Lopunny reference MANY things, like the markings of the Blanc de Hotot, a french breed made for fashion purposes. One of the things they reference is The Velveteen Rabbit, a story about a bunny doll that becomes a real rabbit after learning how to feel true love for its owner, much like how Buneary evolve.
However, after evolving from the ragdoll-looking Buneary, Lopunny look like
>>54449803 instead of a genuine rabbit- but they also vaguely remind you of Playboy Bunnies, who are the type of women who get called "dolls".
So I guess it wouldn't be crazy to say that Lopunny are sort of a joke about "real dolls" (sex dolls).