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Woman are just picky bitches. If you're not rich or extra fit (actually you need to be both) they'll ignore you. It's so easy for them now, five minutes on an app and you're dropped. Even fat ugly girls can change boyfriend once a month if they want to.
So I understand your brother for not being interested by women.
But holy shit threaten him with something scary enough to make him clean his room and stop being a fat shit.
Being fakely happy about being fat is a woman thing, I hate it.