>>141356In my opinion, from easiest to most difficult/annoying:
>BustedTainted Cain (I think they nerfed him though)
Isaac
Tainted Lilith
Tainted Isaac
Tainted Bethany
Tainted Keeper
>EasyTainted Judas
Tainted Lost
Lilith
Judas
>Easy once you get used to the gimmickTainted Magdalene
Tainted Eve
Tainted Apollyon (apparently they buffed his locusts with a bunch of unique effects, might be even easier now)
Tainted Samson
Tainted Azazel
Tainted Forgotten
Judas
>Not particularly difficultTainted Eden
Magdalene
Eve
Samson
Blue Baby
>AnnoyingTainted Lazarus
Tainted Blue Baby
Tainted Jacob
Apollyon
A lot of the tainted variants are just fun/different rather than being difficult, I wouldn't do all the easy and fun ones up front or it'lll become a slog after you get through them. Similarly since you haven't done any alt-path Mother kills for these, I'd try and balance it out because I ended up in the same situation where I had to do a bunch of Hush/Mother/Dogma kills at the very end and it was repetitive as shit. At least you've got most of the Ultra Greed kills done.
t. RPG with vanilla Lost in Rebirth and DG in Repentance